Acute Liver Failure in a Pediatric Patient with Congenital Dyserythropoietic Anemia Type I Treated with Deferasirox | Zendy

Galina Ling | Zendy; Vered Pinsk | Zendy; Inbal GolanTripto | Zendy; Eduard Ling | Zendy

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Acute Liver Failure in a Pediatric Patient with Congenital Dyserythropoietic Anemia Type I Treated with Deferasirox

Author(s) -

Galina Ling,

Vered Pinsk,

Inbal GolanTripto,

Eduard Ling

Publication year - 2015

Publication title -

hematology reports

Language(s) - English

Resource type - Journals

ISSN - 2038-8330

DOI - 10.4081/hr.2015.5987

Subject(s) - deferasirox , medicine , hemolysis , ineffective erythropoiesis , anemia , pediatrics , gastroenterology , thalassemia , erythropoiesis

Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment

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