Open AccessImmunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses
Author(s) -
Luís Otávio Carvalho de Moraes,
Fábio Redivo Lodi,
Thiago Simão Gomes,
Celina Tizuko Fujiyama Oshima,
Sérgio Ricardo Marques,
Carmen Lúcia Penteado Lancellotti,
J.F. Rodriguez-Vázquez,
J.R. Mérida-Velasco,
Luís Garcia Alonso
Publication year - 2011
Publication title -
european journal of histochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 42
eISSN - 2038-8306
pISSN - 1121-760X
DOI - 10.4081/ejh.2011.e24
Subject(s) - immunohistochemistry , temporomandibular joint , anatomy , fetus , pathology , collagen fiber , gestational age , medicine , biology , pregnancy , genetics
The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federal de Uberaba with gestational ages from 17 to 24 weeks were studied. The gestational age of the foetuses was determined by measuring the crown-rump (CR) length. Macroscopically, the foetuses were fixed in 10% formalin solution and dissected by removing the skin and subcutaneous tissue and exposing the deep structures. Immunohistochemical markers of type I and III were used to characterize the existence of collagen fibres. Analysis of the immunohistochemical markers of types I and III collagen revealed the presence of heterotypical fibril networks
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