Clinical picture, diagnosis and treatment of rosacea, complicated by Demodex mites

The article analyzes the clinical picture and course of rosacea in patients with mites. It presents the advantages of using the method of confocal laser scanning microscopy over the method of light microscopy of facial skin scrapes. The aimes were to study the influence of mites on the clinical picture and course of rosacea; to compare laboratory and instrumental diagnostic methods for detecting mites; to evaluate the effectiveness of external therapy aimed at eliminating mites. 212 people were examined. The study included healthy patients, patients with a diagnosis of rosacea with the presence and absence of . The presence of mites was confirmed by two methods of study (light microscopy of skin scrapes and confocal laser scanning microscopy). mites promote the development of acute-inflammatory morphological elements, increase the duration of the condition (more than 5 years, P<0.01) and the probability of recurrence (from 1 to 3 relapses in 39.5% of patients, P<0.05), resulting in a decrease in the quality of life of patients (dermatology life quality index is 12.5±4.5, P<0.05). Antiparasitic drug ivermectin, in the form of an external form, at a concentration of 1% has a high therapeutic efficacy (in 93.3% of cases). folliculorum shows signs of parasitism, while folliculorum brevis is a saprophyte. The severity of the condition does not depend on the quantitative load of the mites in the scrape. As an antiparasitic drug, it is recommended to use 1% ivertmectin.