Signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach | Zendy

Özgür Gündüz | Zendy; Mehmet Ali Can Emeksiz | Zendy; Pınar Atasoy | Zendy; Mehtap Kıdır | Zendy; Selim Yalçın | Zendy; Serkan Demirkan | Zendy

Open Access

Signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach

Author(s) -

Özgür Gündüz,

Mehmet Ali Can Emeksiz,

Pınar Atasoy,

Mehtap Kıdır,

Selim Yalçın,

Serkan Demirkan

Publication year - 2017

Publication title -

dermatology reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.183

H-Index - 10

eISSN - 2036-7406

pISSN - 2036-7392

DOI - 10.4081/dr.2016.6819

Subject(s) - medicine , malignancy , asymptomatic , signet ring cell , pathology , cancer , signet ring cell carcinoma , metastasis , adenocarcinoma , gastric adenocarcinoma , head and neck , skin cancer , dermatology , surgery

Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient’s head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed

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