Treatment of primary cutaneous anaplastic large cell lymphoma with superficial X-rays | Zendy

Malene E. Jepsen | Zendy; Robert Gniadecki | Zendy

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Treatment of primary cutaneous anaplastic large cell lymphoma with superficial X-rays

Author(s) -

Malene E. Jepsen,

Robert Gniadecki

Publication year - 2015

Publication title -

dermatology reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.183

H-Index - 10

eISSN - 2036-7406

pISSN - 2036-7392

DOI - 10.4081/dr.2015.5888

Subject(s) - medicine , nuclear medicine , radiation therapy , lymphoma , complete remission , dermatology , radiology , chemotherapy , surgery , pathology

The optimal radiation schedule for primary cutaneous anaplastic lymphoma (PCALCL) has not been investigated. We report here satisfactory outcomes of low-dose (16-20 Gy, 3-5 fractions), superficial X-ray radiation (40-50 kV) in a series of 10 patients with PCALCL. Only 1 patient developed a local relapse during the median observation time of 25 months; complete remission was recorded in the other patients. This observation indicates that superficial, low dose X-ray therapy may provide a cost-effective alternative to the traditional 35-45 Gy schedules

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