The Clinical Response of West Nile Virus Neuroinvasive Disease to Intravenous Immunoglobulin Therapy | Zendy

Zvi Shimoni | Zendy; Hanna Bin | Zendy; Shlomo Bulvik | Zendy; Mark Niven | Zendy; Rawi Hazzan | Zendy; Ella Mendelson | Zendy; Paul Froom | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The Clinical Response of West Nile Virus Neuroinvasive Disease to Intravenous Immunoglobulin Therapy

Author(s) -

Zvi Shimoni,

Hanna Bin,

Shlomo Bulvik,

Mark Niven,

Rawi Hazzan,

Ella Mendelson,

Paul Froom

Publication year - 2012

Publication title -

clinics and practice

Language(s) - English

Resource type - Journals

ISSN - 2039-7283

DOI - 10.4081/cp.2012.e18

Subject(s) - medicine , west nile virus , disease , antibody , gamma globulin , virus , virology , pediatrics , immunology

The aim of the study was to determine whether intravenous gamma globulin (IVIG) treatment is effective in patients with West Nile Virus (WNV) neuroinvasive disease. We contacted hospital based infectious disease experts in Israeli hospitals to identify patients with WNV neuroinvasive disease who were treated with IVIG. The main outcome measure was neurological response after treatment. There were 12 patients who received IVIG and four improved within 48 h. Three patients died, 6 had partial recovery, and 3 recovered completely. Eleven of the 12 patients were infected with Israeli genotypes that are highly homologous to Europe/Africa viruses. The rapid response in some patients suggests that IVIG is effective, and might be used to treat patients with WNV neuroinvasive disease with IVIG

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research