Hepatic Sarcoidosis in a Patient with Chronic Hepatitis B Virus Infection
Author(s) -
Hye-Sun Park,
Hye Min Kim,
Ji-Yeon Lee,
Su-Young Jung,
Seung-Hee Han,
YongBeom Park,
Soo-Kon Lee,
Sang Hoon Ahn,
SangWon Lee
Publication year - 2015
Publication title -
journal of rheumatic diseases
Language(s) - English
Resource type - Journals
eISSN - 2093-940X
pISSN - 2233-4718
DOI - 10.4078/jrd.2015.22.3.200
Subject(s) - sarcoidosis , medicine , chronic hepatitis , virology , hepatitis b virus , virus , immunology , pathology
Sarcoidosis is a systemic inflammatory granulomatous disease affecting multiple organs, including liver, spleen, heart, eyes, and skin. Liver involvement is reported in 11.5% of cases and many studies have reported on the association between hepatitis C virus infection and sarcoidosis. However, the role of hepatitis B virus (HBV) infection as a trigger for sarcoidosis has never been reported. We describe a case of hepatic sarcoidosis in a patient with chronic hepatitis B infection, with a possible link between the two. It is the first case report of a patient with interferon-α-naïve chronic HBV infection presenting with hepatic sarcoidosis accompanied by portal hypertension and liver cirrhosis. (J Rheum Dis 2015;22:200-204)
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