A Case of Secondary Gout Associated with Essential Thrombocythemia | Zendy

Young Min Kim | Zendy; Sora Lee | Zendy; Ji Eun Lee | Zendy; Do Hyoung Lim | Zendy; Il Kim | Zendy; Keon Woo Park | Zendy; Soon Il Lee | Zendy

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A Case of Secondary Gout Associated with Essential Thrombocythemia

Author(s) -

Young Min Kim,

Sora Lee,

Ji Eun Lee,

Do Hyoung Lim,

Il Kim,

Keon Woo Park,

Soon Il Lee

Publication year - 2012

Publication title -

journal of rheumatic diseases

Language(s) - English

Resource type - Journals

eISSN - 2093-940X

pISSN - 2233-4718

DOI - 10.4078/jrd.2012.19.1.47

Subject(s) - gout , essential thrombocythemia , hyperuricemia , medicine , thrombocytosis , uric acid , myeloproliferative disorders , arthritis , gastroenterology , polycythemia vera , platelet

Gouty arthritis is a metabolic disorder characterized by hyperuricemia, deposition of monosodium urate crystal in the joints, and recurrent episodes of acute inflammatory arthritis. Depending on the actual causes of hyperuricemia, gout is classified as primary or secondary gout. In myeloproliferative neoplasms, a turnover of nucleic acids is greatly augmented and therefore the blood concentration of uric acid may be markedly increased. But an acute attack of gout is extremely rare in patients with myeloproliferative neoplasms. Essential thrombocythemia, one of the myeloproliferative neoplasms, is characterized by megakaryocytic hyperplasia in bone marrow and marked thrombocytosis. We report a case of secondary gout in a 66-year-old man with essential thrombocythemia.

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