Dicer Functions in Aquatic Species | Zendy

Yasuko Kitagishi | Zendy; Naoko Okumura | Zendy; Hitomi Yoshida | Zendy; Chika Tateishi | Zendy; Yuri Nishimura | Zendy; Satoru Matsuda | Zendy

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Dicer Functions in Aquatic Species

Author(s) -

Yasuko Kitagishi,

Naoko Okumura,

Hitomi Yoshida,

Chika Tateishi,

Yuri Nishimura,

Satoru Matsuda

Publication year - 2011

Publication title -

journal of amino acids

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.188

H-Index - 5

eISSN - 2090-0112

pISSN - 2090-0104

DOI - 10.4061/2011/782187

Subject(s) - dicer , ribonuclease iii , rna , rna interference , nucleic acid , rnase p , biology , microbiology and biotechnology , small interfering rna , rna silencing , computational biology , genetics , gene

Dicer is an RNase III enzyme with two catalytic subunits, which catalyzes the cleavage of double-stranded RNA to small interfering RNAs and micro-RNAs, which are mainly involved in invasive nucleic acid defense and endogenous genes regulation. Dicer is abundantly expressed in embryos, indicating the importance of the protein in early embryonic development. In addition, Dicer is thought to be involved in defense mechanism against foreign nucleic acids such as viruses. This paper will mainly focus on the recent progress of Dicer-related research and discuss potential RNA interference pathways in aquatic species.

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