Inflammation and Parkinson's Disease | Zendy

Carlos Barcia | Zendy; Stéphane Hunot | Zendy; Gilles J. Guillemin | Zendy; Fernando J. Pitossi | Zendy

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Inflammation and Parkinson's Disease

Author(s) -

Carlos Barcia,

Stéphane Hunot,

Gilles J. Guillemin,

Fernando J. Pitossi

Publication year - 2011

Publication title -

parkinson s disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.748

H-Index - 46

eISSN - 2090-8083

pISSN - 2042-0080

DOI - 10.4061/2011/729054

Subject(s) - neuroinflammation , neuroprotection , medicine , neurodegeneration , parkinson's disease , clinical trial , disease , cyclooxygenase , pharmacology , inflammation , in vivo , neuroscience , bioinformatics , intensive care medicine , immunology , psychology , biology , biochemistry , microbiology and biotechnology , enzyme

Parkinson's disease is a neurodegenerative disorder associated with aging characterized by a motor extrapiramidal alteration secondary to the progressive death of dopaminergic neurons of the substantia nigra pars compacta. The cause of this neuronal loss remains unknown but post mortem studies on brains of parkinsonian patients showed high index of inflammatory mechanism markers. This point has gone to open new lines of research in order to ascertain what role have these inflammatory process in neuronal degeneration and has opened new therapeutic possibilities to stop or at least to brake the neurodegenerative process.

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