Hereditary Connective Tissue Diseases in Young Adult Stroke: A Comprehensive Synthesis | Zendy

Olivier Vanakker | Zendy; Dimitri Hemelsoet | Zendy; Anne De Paepe | Zendy

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Hereditary Connective Tissue Diseases in Young Adult Stroke: A Comprehensive Synthesis

Author(s) -

Olivier Vanakker,

Dimitri Hemelsoet,

Anne De Paepe

Publication year - 2011

Publication title -

stroke research and treatment

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.939

H-Index - 34

eISSN - 2090-8105

pISSN - 2042-0056

DOI - 10.4061/2011/712903

Subject(s) - medicine , stroke (engine) , connective tissue , disease , pathogenesis , pathology , bioinformatics , intensive care medicine , mechanical engineering , engineering , biology

Though the genetic background of ischaemic and haemorrhagic stroke is often polygenetic or multifactorial, it can in some cases result from a monogenic disease, particularly in young adults. Besides arteriopathies and metabolic disorders, several connective tissue diseases can present with stroke. While some of these diseases have been recognized for decades as causes of stroke, such as the vascular Ehlers-Danlos syndrome, others only recently came to attention as being involved in stroke pathogenesis, such as those related to Type IV collagen. This paper discusses each of these connective tissue disorders and their relation with stroke briefly, emphasizing the main clinical features which can lead to their diagnosis

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