Treatment of Severe Metastatic Calcification and Calciphylaxis in Dialysis Patients | Zendy

Saurabh Goel | Zendy; Keith Bellovich | Zendy; Peter A. McCullough | Zendy

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Treatment of Severe Metastatic Calcification and Calciphylaxis in Dialysis Patients

Author(s) -

Saurabh Goel,

Keith Bellovich,

Peter A. McCullough

Publication year - 2011

Publication title -

international journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.551

H-Index - 29

eISSN - 2090-2158

pISSN - 2090-214X

DOI - 10.4061/2011/701603

Subject(s) - calciphylaxis , medicine , dialysis , intensive care medicine , sodium thiosulfate , complication , calcification , surgery , inorganic chemistry , chemistry

Metastatic calcification is a frequent complication encountered in patients undergoing maintenance dialysis and has a complex pathogenesis. It is often difficult to treat and is associated with high morbidity and mortality. Early recognition and prompt initiation of treatment is vital. Local wound care and aggressive metabolic control remain the cornerstones of the therapy. Various novel treatment strategies including sodium thiosulfate and hyperbaric oxygen therapy have been utilized and reviewed in this paper. The response rate to treatment is poor and prevention is the best approach

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