Open AccessRight Ventricular Dysfunction and Failure in Chronic Pressure Overload
Author(s) -
Marc A. Simon,
Michael R. Pinsky
Publication year - 2011
Publication title -
cardiology research and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 35
eISSN - 2090-8016
pISSN - 2090-0597
DOI - 10.4061/2011/568095
Subject(s) - medicine , pathophysiology , pressure overload , pulmonary hypertension , intensive care medicine , cardiology , heart failure , volume overload , cardiac hypertrophy
Right ventricular (RV) dysfunction is the main cause of death in pulmonary arterial hypertension (PAH). Our understanding of the pathophysiology of RV dysfunction is limited but improving. Methods to better diagnose RV dysfunction earlier and treatments specifically designed to minimize or reverse the remodeling process are likely to improve outcomes. We review the current understanding of RV dysfunction in chronic pressure overload and introduce some novel insights based on recent investigations into pathophysiology, diagnosis, and treatment
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