What is Next for the Genetics of Multiple Sclerosis?
Author(s) -
Sreeram V. Ramagopalan,
David A. Dyment
Publication year - 2011
Publication title -
autoimmune diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.681
H-Index - 32
eISSN - 2090-0422
pISSN - 2090-0430
DOI - 10.4061/2011/519450
Subject(s) - multiple sclerosis , medicine , computational biology , biology , psychiatry
We review here our current understanding of the genetic aetiology of the common complex neurological disease multiple sclerosis (MS). The strongest genetic risk factor for MS is the major histocompatibility complex which was identified in the 1970s. In 2011, after a number of genome-wide association studies have been completed and have identified approximately 20 new genes for MS, we ask the question—what is next for the genetics of MS
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