Issues Related to Sentinel Lymph Node Assessment in the Management of Breast Cancer—What Are Relevant in Pathology Reports?
Author(s) -
Patricia Tai,
Kurian Joseph,
Edward Yu
Publication year - 2011
Publication title -
pathology research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.398
H-Index - 21
eISSN - 2090-8091
pISSN - 2042-003X
DOI - 10.4061/2011/504940
Subject(s) - medicine , breast cancer , sentinel node , dissection (medical) , axillary dissection , biopsy , axillary lymph node dissection , lymph node , radiology , axilla , sentinel lymph node , metastasis , cancer , general surgery , pathology
Most cancer centers now perform sentinel node (SN) biopsies. The limited number of SNs sampled compared with an axillary dissection has allowed more comprehensive lymph node analysis resulting in increased detection of micrometastases. Many node-negative cases are now reclassified as micrometastatic. Recent research on SN biopsy focuses on whether axillary dissection is always necessary when the SN is positive. Some subgroups of patients have a higher risk of more nodal metastases when completion axillary dissections were performed. This paper summarizes the different studies and examines what are the clinically relevant items to report on SN node pathology: volume or size of nodal metastasis, location within the node, extranodal extension, number of involved SN(s) and non-SN(s), total number of SN, and total number of nodes on axillary dissection, if performed.
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