Effect of Therapy by Using Advocate Spot-On Combination (Imidacloprid 10% and Moxidectin 2.5%) on Subcutaneous Dirofilariosis in Dogs | Zendy

Radmila Dobešová Paran | Zendy; Vlasta Svobodová | Zendy

Open Access

Effect of Therapy by Using Advocate Spot-On Combination (Imidacloprid 10% and Moxidectin 2.5%) on Subcutaneous Dirofilariosis in Dogs

Author(s) -

Radmila Dobešová Paran,

Vlasta Svobodová

Publication year - 2011

Publication title -

veterinary medicine international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.62

H-Index - 30

eISSN - 2090-8113

pISSN - 2042-0048

DOI - 10.4061/2011/482746

Subject(s) - dirofilaria repens , moxidectin , imidacloprid , medicine , repens , dirofilaria immitis , veterinary medicine , anesthesia , biology , helminths , anthelmintic , immunology , botany , agronomy , pesticide

Dirofilaria (Nochtiella) repens is a filarioid parasite that causes subcutaneous dirofilariosis in dogs. Adults, while localized in subcutaneous tissues, lay embryos (microfilariae (mf)) into the blood stream of dogs, which constitute a reservoir for infection of other definitive or accidental hosts as humans. This study was carried out to assess the efficacy of spot-on combination of imidacloprid and moxidectin on microfilariaemia in naturally infected dogs. A group of 11 dogs was monthly examined for the presence of microfilariae in peripheral blood by modified Knott's test method. Treatment was administered monthly for 4 months. All dogs (i.e., 100%) became negative for microfilariaemia throughout the study. These results confirm the effect of the combination of imidacloprid and moxidectin on D. (Nochtiella) repens

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