Beneficial Regulation of Matrix Metalloproteinases for Skin Health | Zendy

Neena Philips | Zendy; Susan Auler | Zendy; Raul Hugo | Zendy; Salvador González | Zendy

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Beneficial Regulation of Matrix Metalloproteinases for Skin Health

Author(s) -

Neena Philips,

Susan Auler,

Raul Hugo,

Salvador González

Publication year - 2011

Publication title -

enzyme research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.439

H-Index - 39

eISSN - 2090-0406

pISSN - 2090-0414

DOI - 10.4061/2011/427285

Subject(s) - matrix metalloproteinase , extracellular matrix , scars , downregulation and upregulation , wound healing , medicine , cancer research , immunology , pathology , chemistry , biology , microbiology and biotechnology , biochemistry , gene

Matrix metalloproteinases (MMPs) are essential to the remodeling of the extracellular matrix. While their upregulation facilitates aging and cancer, they are essential to epidermal differentiation and the prevention of wound scars. The pharmaceutical industry is active in identifying products that inhibit MMPs to prevent or treat aging and cancer and products that stimulate MMPs to prevent epidermal hyperproliferative diseases and wound scars

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