Synchronous Presence of Nasopharyngeal Carcinoma and Marginal Zone (MALT-Type) B-Cell Lymphoma in the Pharynx
Author(s) -
Triantafyllia Κoletsa,
Georgios Petrakis,
Georgia Karayannopoulou,
Dimitrios Pappas,
Konstantinos Markou,
Georgios Karkavelas,
Ioannis Kostopoulos
Publication year - 2011
Publication title -
pathology research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.398
H-Index - 21
eISSN - 2090-8091
pISSN - 2042-003X
DOI - 10.4061/2011/340763
Subject(s) - medicine , pharynx , nasopharyngeal carcinoma , pathology , lymphoma , malignancy , carcinoma , biopsy , malt lymphoma , radiation therapy , radiology , anatomy
Synchronous malignancy of squamous cell carcinoma and malignant lymphoma in the head and neck region is extremely rare. Nasopharyngeal carcinoma is a nonlymphomatous, squamous cell carcinoma that occurs in the nasopharyngeal epithelium. Reported herein is a unique case of nasopharyngeal carcinoma occurring simultaneously with MALT-type lymphoma in an 83-year-old woman, who complained of deglutition dysfunction. Endoscopic examination of respective organs revealed a submucosal tumour on the posterior wall of pharynx. Biopsy of the hypopharynx was taken and sent for histological examination, which revealed two different neoplasms. Immunohistochemical and molecular analysis confirmed the diagnosis of nasopharyngeal carcinoma coexisting with a MALT-type lymphoma.
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