Understanding and Targeting the Wnt/β-Catenin Signaling Pathway in Chronic Leukemia | Zendy

Sharmilan Thanendrarajan | Zendy; Y. Kim | Zendy; Ingo G.H. SchmidtWolf | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Understanding and Targeting the Wnt/β-Catenin Signaling Pathway in Chronic Leukemia

Author(s) -

Sharmilan Thanendrarajan,

Y. Kim,

Ingo G.H. SchmidtWolf

Publication year - 2011

Publication title -

leukemia research and treatment

Language(s) - English

Resource type - Journals

eISSN - 2090-3219

pISSN - 2090-3227

DOI - 10.4061/2011/329572

Subject(s) - wnt signaling pathway , leukemia , cancer research , catenin , signal transduction , medicine , beta catenin , biology , immunology , microbiology and biotechnology

It has been revealed that the Wnt/ β -catenin signaling pathway plays an important role in the development of solid tumors and hematological malignancies, particularly in B-cell neoplasia and leukemia. In the last decade there have been made experimental approaches targeting the Wnt pathway in chronic leukemia. In this paper we provide an overview about the current state of knowledge regarding the Wnt/ β -catenin signaling pathway in chronic leukemia with special focus on therapeutic options and strategies.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research