Benefits from Treatment and Control of Patients with Resistant Hypertension
Author(s) -
Michael Doumas,
Vasilios Papademetriou,
Στέλλα Δούμα,
Charles Faselis,
Konstantinos Tsioufis,
Eugene Gkaliagkousi,
Konstantinos Petidis,
Chrysanthos Zamboulis
Publication year - 2010
Publication title -
international journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.744
H-Index - 37
eISSN - 2090-0392
pISSN - 2090-0384
DOI - 10.4061/2011/318549
Subject(s) - medicine , blood pressure , resistant hypertension , baroreceptor , intensive care medicine , denervation , observational study , modalities , lifestyle modification , cardiology , disease , heart rate , social science , sociology
Resistant hypertension is commonly found in everyday clinical practice. However, the risks of resistant hypertension, as well as the benefits of treatment and control of blood pressure in patients with resistant hypertension remain vaguely clarified. Data from small clinical studies and observational cohorts suggest that patients with resistant hypertension are at increased cardiovascular risk, while control of blood pressure offers substantial benefits. It has to be noted however that data from appropriate large randomized studies are missing, and resistant hypertension remains remarkably understudied. Resistant hypertension has attracted significant scientific interest lately, as new therapeutic modalities become available. The interventional management of resistant hypertension either by carotid baroreceptor stimulation or renal sympathetic denervation is currently under investigation with promising preliminary results. This review presents available evidence regarding the benefits of treatment and control of blood pressure in patients with resistant hypertension and offers a critical evaluation of existing data in this field
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