Pulmonary Hypertension in Dialysis Patients: A Cross-Sectional Italian Study
Author(s) -
Fabio Fabbian,
Stefano Cantelli,
Christian Molino,
Marco Pala,
C Longhini,
Francesco Portaluppi
Publication year - 2010
Publication title -
international journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.551
H-Index - 29
eISSN - 2090-2158
pISSN - 2090-214X
DOI - 10.4061/2011/283475
Subject(s) - medicine , cross sectional study , dialysis , pulmonary hypertension , intensive care medicine , pediatrics , pathology
. Pulmonary hypertension (PHT) is an independent predictor of mortality. The aim of this study was to relate pulmonary arterial pressure (PAP) to the cardiovascular status of dialysis patients. Methods. 27 peritoneal dialysis (PD) and 29 haemodialysis (HD) patients ( years, 37 males, dialysis vintage was months) had PAP measured by echocardiography. Clinical and laboratory data of the patients were recorded. Results. PHT ( mmHg) was detected in 22 patients (39%; PAP mmHg) and was diagnosed in 18.5% of PD patients and 58.6% of HD patients (). The group of subjects with PH had higher dialysis vintage ( versus months, ), interdialytic weight gain ( versus Kg, ), lower diastolic blood pressure ( versus mmHg, ) and ejection fraction ( versus %, ) than the patients with normal PAP. PAP was correlated positively with diastolic left ventricular volume (, ) and negatively with ejection fraction (, ). PHT was independently associated with dialysis vintage (OR 1.022, 95% CI 1.002–1.041, ) and diastolic blood pressure (OR 0.861, 95% CI 0.766–0.967, ). Conclusions. PHT is frequent in dialysis patients, it appears to be a late complication of HD treatment, mainly related to cardiac performance and cardiovascular disease history
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom