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Electric Field Analysis of Breast Tumor Cells
Author(s) -
Gowri Sree Varadarajan,
K. Udayakumar,
R. Sundararajan
Publication year - 2011
Publication title -
international journal of breast cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.552
H-Index - 15
eISSN - 2090-3170
pISSN - 2090-3189
DOI - 10.4061/2011/235926
Subject(s) - electric field , medicine , breast tumor , pulse (music) , biomedical engineering , drug delivery , chemotherapy , tumor cells , distribution (mathematics) , field (mathematics) , radiation therapy , pathology , cancer research , surgery , breast cancer , optics , materials science , nanotechnology , cancer , physics , pure mathematics , mathematical analysis , mathematics , quantum mechanics , detector
An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this.

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