Drug-Induced Bullous Sweet Syndrome with Multiple Autoimmune Features
Author(s) -
Jared J. Lund,
Erik J. Stratman,
Deepa Jose,
Ling Xia,
Donald A. Wilson,
Mohammed Moizuddin
Publication year - 2010
Publication title -
autoimmune diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.681
H-Index - 32
eISSN - 2090-0422
pISSN - 2090-0430
DOI - 10.4061/2010/176749
Subject(s) - medicine , relapsing polychondritis , anti nuclear antibody , vasculitis , carbamazepine , antibody , immunology , anti neutrophil cytoplasmic antibody , glomerulonephritis , autoantibody , drug , sweet syndrome , dermatology , pathology , disease , pharmacology , epilepsy , kidney , psychiatry
Sweet syndrome (SS) (Acute Febrile Neutrophilic Dermatosis) has been reported in association with autoimmune phenomena including relapsing polychondritis, drug-induced lupus, and the development of antineutrophil cytoplasmic antibodies (ANCAs). However, a combination of these autoimmune features has not been reported. Herein, we report a case of drug-induced bullous SS with ocular and mucosal involvement, glomerulonephritis, and multiple autoimmune features including clinical polychondritis with antitype II collagen antibodies, ANCAs, antinuclear (HEp-2), and antihistone antibodies in a patient on hydralazine and carbamazepine.
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