Profile of Hashimoto's Thyroiditis in Sri Lankans: Is There an Increased Risk of Ancillary Pathologies in Hashimoto's Thyroiditis?
Author(s) -
E. H. Siriweera,
Neelakanthi Ratnatunga
Publication year - 2010
Publication title -
journal of thyroid research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 31
eISSN - 2090-8067
pISSN - 2042-0072
DOI - 10.4061/2010/124264
Subject(s) - medicine , thyroiditis , thyroid lymphoma , hashimoto disease , thyroid , anti thyroid autoantibodies , pathology , adenoma , follicular cell , gastroenterology , immunology , autoantibody , antibody
Hashimoto's thyroiditis has been reported to be associated with many neoplastic and nonneoplastic thyroid pathologies. This retrospective study aims to determine the demographic profile of Hashimoto's thyroiditis in Sri Lankans, document ancillary pathologies in Hashimoto's thyroiditis, and determine whether there is an increased risk of occurrence of malignancies, benign neoplasms, and nonneoplastic benign lesions in Hashimoto's thyroiditis by comparing with thyroids showing multinodular goiters, follicular adenomas, and colloid nodules. The mean age of Hashimoto's thyroiditis is 43.3 years with the majority in the 41 to 60 year age group and a female to male ratio of 10.3 : 1. This study revealed a statistically significant increase of thyroid malignancies in association with Hashimoto's thyroiditis. The association of Papillary carcinoma, Non-Hodgkin's lymphoma, and Hurthle cell adenoma with Hashimoto's thyroiditis was statistically significant.
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