Increased Density of the Liver and Amiodarone-Associated Phospholipidosis | Zendy

Sunao Kojima | Zendy; Shinobu Kojima | Zendy; Hirofumi Ueno | Zendy; Motohiro Takeya | Zendy; Hisao Ogawa | Zendy

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Increased Density of the Liver and Amiodarone-Associated Phospholipidosis

Author(s) -

Sunao Kojima,

Shinobu Kojima,

Hirofumi Ueno,

Motohiro Takeya,

Hisao Ogawa

Publication year - 2009

Publication title -

cardiology research and practice

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 35

eISSN - 2090-8016

pISSN - 2090-0597

DOI - 10.4061/2009/598940

Subject(s) - amiodarone , phospholipidosis , medicine , liver biopsy , liver steatosis , biopsy , radiology , cardiomyopathy , elevated liver enzymes , computed tomographic , cardiology , gastroenterology , computed tomography , fatty liver , atrial fibrillation , heart failure , disease , phospholipid , membrane , biology , genetics , pregnancy

This is a case report in which a 60-year-old man who suffered from ventricular tachycardia with dilated cardiomyopathy was prescribed amiodarone. After taking amiodarone, liver enzymes were increased and computed tomographic (CT) scanning of the abdomen showed a significant increase in the density of the liver without contrast medium. He was suspected as hemochromatosis and liver biopsy was performed. An abnormal high density of liver tissue may be observed in an unenhanced CT in patients treated with amiodarone and we suggest that periodic monitoring of liver function and/or liver biopsy is warranted before an irreversible stage is reached.

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