The complete genome sequence of Clostridium indolis DSM 755T
Author(s) -
Amy S. Biddle,
Susan Leschine,
Marcel Huntemann,
James Han,
Amy Chen,
Nikos C. Kyrpides,
Victor Markowitz,
Krishna Palaniappan,
Natalia Ivanova,
Natalia Mikhailova,
Galina Ovchinnikova,
Andrew J. Schaumberg,
Amrita Pati,
Dimitrios Stamatis,
T. B. K. Reddy,
Elizabeth A. Lobos,
Lynne Goodwin,
Henrik Nordberg,
Michael Cantor,
Susan X. Hua,
Tanja Woyke,
Jeffrey L. Blanchard
Publication year - 2014
Publication title -
standards in genomic sciences
Language(s) - English
Resource type - Journals
ISSN - 1944-3277
DOI - 10.4056/sigs.5281010
Subject(s) - whole genome sequencing , biology , sequence (biology) , genome , clostridium , genetics , computational biology , evolutionary biology , microbiology and biotechnology , bacteria , gene
Clostridium indolis DSM 755(T) is a bacterium commonly found in soils and the feces of birds and mammals. Despite its prevalence, little is known about the ecology or physiology of this species. However, close relatives, C. saccharolyticum and C. hathewayi, have demonstrated interesting metabolic potentials related to plant degradation and human health. The genome of C. indolis DSM 755(T) reveals an abundance of genes in functional groups associated with the transport and utilization of carbohydrates, as well as citrate, lactate, and aromatics. Ecologically relevant gene clusters related to nitrogen fixation and a unique type of bacterial microcompartment, the CoAT BMC, are also detected. Our genome analysis suggests hypotheses to be tested in future culture based work to better understand the physiology of this poorly described species.
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