Open AccessComplete Genome Sequence of a thermotolerant sporogenic lactic acid bacterium, Bacillus coagulans strain 36D1
Author(s) -
Mun Su Rhee,
Brélan E. Moritz,
Gary Xie,
Tijana Glavina Del Rio,
Eileen Dalin,
Hope Tice,
David Bruce,
Lynne Goodwin,
Olga Chertkov,
Thomas Brettin,
C. S. Han,
Chris Detter,
Sam Pitluck,
Miriam Land,
Milind Patel,
Mark Ou,
Roberta Harbrucker,
L. O. Ingram,
K. T. Shanmugam
Publication year - 2011
Publication title -
standards in genomic sciences
Language(s) - English
Resource type - Journals
ISSN - 1944-3277
DOI - 10.4056/sigs.2365342
Subject(s) - bacillus coagulans , lactic acid , bacteria , xylose , strain (injury) , hemicellulose , biology , probiotic , whole genome sequencing , cellulose , fermentation , food science , biochemistry , microbiology and biotechnology , genome , chemistry , gene , genetics , anatomy
Bacillus coagulans is a ubiquitous soil bacterium that grows at 50-55 °C and pH 5.0 and ferments various sugars that constitute plant biomass to L (+)-lactic acid. The ability of this sporogenic lactic acid bacterium to grow at 50-55 °C and pH 5.0 makes this organism an attractive microbial biocatalyst for production of optically pure lactic acid at industrial scale not only from glucose derived from cellulose but also from xylose, a major constituent of hemicellulose. This bacterium is also considered as a potential probiotic. Complete genome sequence of a representative strain, B. coagulans strain 36D1, is presented and discussed.
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