The IGS Standard Operating Procedure for Automated Prokaryotic Annotation | Zendy

Kevin Galens | Zendy; Joshua Orvis | Zendy; Sean C. Daugherty | Zendy; Heather H. Creasy | Zendy; Samuel V. Angiuoli | Zendy; Owen White | Zendy; Jennifer R. Wortman | Zendy; Anup Mahurkar | Zendy; Michelle Giglio | Zendy

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The IGS Standard Operating Procedure for Automated Prokaryotic Annotation

Author(s) -

Kevin Galens,

Joshua Orvis,

Sean C. Daugherty,

Heather H. Creasy,

Samuel V. Angiuoli,

Owen White,

Jennifer R. Wortman,

Anup Mahurkar,

Michelle Giglio

Publication year - 2011

Publication title -

standards in genomic sciences

Language(s) - English

Resource type - Journals

ISSN - 1944-3277

DOI - 10.4056/sigs.1223234

Subject(s) - annotation , pipeline (software) , visualization , genome , computer science , coding (social sciences) , computational biology , genome project , biology , information retrieval , data mining , gene , genetics , artificial intelligence , programming language , statistics , mathematics

The Institute for Genome Sciences (IGS) has developed a prokaryotic annotation pipeline that is used for coding gene/RNA prediction and functional annotation of Bacteria and Archaea. The fully automated pipeline accepts one or many genomic sequences as input and produces output in a variety of standard formats. Functional annotation is primarily based on similarity searches and motif finding combined with a hierarchical rule based annotation system. The output annotations can also be loaded into a relational database and accessed through visualization tools.

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