Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis | Zendy

Arianna Bianchi | Zendy; Letizia Marchetti | Zendy; Zoe Hall | Zendy; Henrique Lemos | Zendy; Michèle Vacca | Zendy; Hannah L. Paish | Zendy; Kile Green | Zendy; Bronte Elliott | Zendy; Dina Tiniakos | Zendy; João F. Passos | Zendy; Diana Jurk | Zendy; Derek A. Mann | Zendy; Caroline Wilson | Zendy

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Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis

Author(s) -

Arianna Bianchi,

Letizia Marchetti,

Zoe Hall,

Henrique Lemos,

Michèle Vacca,

Hannah L. Paish,

Kile Green,

Bronte Elliott,

Dina Tiniakos,

João F. Passos,

Diana Jurk,

Derek A. Mann,

Caroline Wilson

Publication year - 2021

Publication title -

the journal of immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.737

H-Index - 372

eISSN - 1550-6606

pISSN - 0022-1767

DOI - 10.4049/jimmunol.2001022

Subject(s) - inflammation , sirtuin , steatosis , sirtuin 1 , nad+ kinase , senescence , carcinogenesis , cancer , medicine , endocrinology , cancer research , biology , biochemistry , downregulation and upregulation , enzyme , gene

Key PointsModerate exercise reduces inflammaging, liver tumors, and chronic liver disease. Key molecular changes include lipid metabolism, oxidative damage, and senescence. Increased NAD + , sirtuin activity, and inflammatory and metabolic reprogramming occur.

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