Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus | Zendy

Corinne J. Smith | Zendy; Vanessa Venturi | Zendy; Máire F. Quigley | Zendy; Holly Turula | Zendy; Emma Gostick | Zendy; Kristin Ladell | Zendy; Brenna J. Hill | Zendy; Danielle Himelfarb | Zendy; Kylie M. Quinn | Zendy; Hui Yee Greenaway | Zendy; Thurston H. Y. Dang | Zendy; Robert A. Seder | Zendy; Daniel C. Douek | Zendy; Ann B. Hill | Zendy; Miles P. Davenport | Zendy; David A. Price | Zendy; Christopher M. Snyder | Zendy

Open Access

Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

Author(s) -

Corinne J. Smith,

Vanessa Venturi,

Máire F. Quigley,

Holly Turula,

Emma Gostick,

Kristin Ladell,

Brenna J. Hill,

Danielle Himelfarb,

Kylie M. Quinn,

Hui Yee Greenaway,

Thurston H. Y. Dang,

Robert A. Seder,

Daniel C. Douek,

Ann B. Hill,

Miles P. Davenport,

David A. Price,

Christopher M. Snyder

Publication year - 2019

Publication title -

the journal of immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.737

H-Index - 372

eISSN - 1550-6606

pISSN - 0022-1767

DOI - 10.4049/jimmunol.1900455

Subject(s) - biology , cd8 , epitope , cytotoxic t cell , population , virology , obligate , subdominant , t cell , cytomegalovirus , chronic infection , immunology , virus , immune system , genetics , microbiology and biotechnology , antibody , viral disease , herpesviridae , ecology , demography , sociology , in vitro

Key PointsClonal stability is a feature of memory inflation. Stochastic expansions maintain clonal stability during memory inflation. Persistent clonotypes are often public in the context of memory inflation.

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