Open AccessG.O.D.’s Holy Grail: Discovery of the RAG Proteins
Author(s) -
Vicky Brandt,
David B. Roth
Publication year - 2008
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.180.1.3
Subject(s) - holy grail , chemistry , microbiology and biotechnology , computational biology , biology , computer science , world wide web
The question of how the immune system can have specificity for a given molecule out of an endless realm of possibilities, sometimes irreverently referred to as the G.O.D. (Generation of Diversity) problem, took nearly a century to answer. Physicians and scientists had long been aware that the immune
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