Open AccessOne for One Peptide Binding to MHC Molecules
Author(s) -
Janice S. Blum
Publication year - 2005
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.175.7.4161
Subject(s) - peptide , major histocompatibility complex , chemistry , computational biology , microbiology and biotechnology , biology , biochemistry , antigen , immunology
B and T lymphocytes recognize Ag in very different contexts. Although B cells typically respond to native Ag, T lymphocytes are capable of recognizing both native and denatured Ag but only in the context of accessory cells. These latter cells, now known as APCs, are critical for T cell activation.
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