Open AccessThe Birth of Molecular Immunology
Author(s) -
Patricia J. Gearhart
Publication year - 2004
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.173.7.4259
Subject(s) - germline , diversity (politics) , biology , computational biology , genetics , gene , evolutionary biology , immunology , political science , law
At the time of publication of a paper by Hozumi and Tonegawa ([1][1]) in 1976, a controversy was raging about the number of germline variable (V) genes and how Ab diversity was generated ([2][2]). Protein sequencing had clearly shown that Abs were divided into two contiguous regions: a V region and
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom