Open AccessTumor-Specific T Cell Activation by Recombinant Immunoreceptors: CD3ζ Signaling and CD28 Costimulation Are Simultaneously Required for Efficient IL-2 Secretion and Can Be Integrated into One Combined CD28/CD3ζ Signaling Receptor Molecule
Author(s) -
Andreas Hombach,
Anja Wieczarkowiecz,
Thomas P. Marquardt,
Claudia Heuser,
Loretta Usai,
C. Pohl,
Barbara Seliger,
Hinrich Abken
Publication year - 2004
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.173.1.695
Subject(s) - cd28 , recombinant dna , microbiology and biotechnology , secretion , cd3 , t cell , biology , immunology , immune system , cd8 , biochemistry , gene
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