Lack of Association between Human Switch Recombination Breakpoints and the Secondary Structure of Targeted DNA Regions
Author(s) -
Qiang PanHammarström,
Yaofeng Zhao,
Lennart Hammarström
Publication year - 2004
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.172.5.2727
Subject(s) - breakpoint , recombination , genetics , dna , association (psychology) , biology , gene , chromosomal translocation , psychology , psychotherapist
As class switch recombination (CSR) is a region, rather than a site-specific event, a relationship between the recombination breakpoints and the structural character of the switch (S) regions involved has been sought. It has earlier been suggested that CSR preferentially occurs at transitions from a
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