PD-1 Blockade Promotes Epitope Spreading in Anticancer CD8+ T Cell Responses by Preventing Fratricidal Death of Subdominant Clones To Relieve Immunodomination
Author(s) -
Arash Memarnejadian,
Courtney Meilleur,
Christopher R. Shaler,
Khashayarsha Khazaie,
Jack R. Bennink,
Todd D. Schell,
S. M. Mansour Haeryfar
Publication year - 2017
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.1700643
Subject(s) - subdominant , blockade , cytotoxic t cell , epitope , cd8 , biology , microbiology and biotechnology , cancer research , immunology , genetics , immune system , antibody , receptor , in vitro
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom