How Thymocytes Achieve Their Fate | Zendy

Dan R. Littman | Zendy

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How Thymocytes Achieve Their Fate

Author(s) -

Dan R. Littman

Publication year - 2016

Publication title -

the journal of immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.737

H-Index - 372

eISSN - 1550-6606

pISSN - 0022-1767

DOI - 10.4049/jimmunol.1600032

Subject(s) - major histocompatibility complex , mhc class ii , subdivision , biology , acquired immune system , t cell , mhc class i , microbiology and biotechnology , immunology , cytotoxic t cell , class (philosophy) , thymocyte , immune system , genetics , computer science , geography , archaeology , artificial intelligence , in vitro

One of the central principles of adaptive immunity is the subdivision of T lymphocytes into functionally distinct subsets. Although multiple T cell subsets were shown in recent years to emerge from the thymus, most mature T cells consist of MHC class II (MHC II)–restricted CD4+ T helper cells and

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