Open AccessTCR Transgenic Mice That Shed Light on Immune and Environmental Regulators in Multiple Sclerosis
Author(s) -
Kathrine E. Attfield,
Lars Fugger
Publication year - 2013
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.1300427
Subject(s) - immune system , t cell receptor , genetically modified mouse , transgene , multiple sclerosis , biology , immunology , microbiology and biotechnology , t cell , genetics , gene
The employment of the animal model experimental autoimmune encephalomyelitis (EAE) to further unravel the multifaceted etiology of multiple sclerosis (MS) has received both acclamation and criticism. The complexity of MS is owing to its association with a repertoire of genetic variants ([1][1]) in
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