Open AccessColonel Bruton's Kinase Defined the Molecular Basis of X-Linked Agammaglobulinemia, the First Primary Immunodeficiency
Author(s) -
Wasif N. Khan
Publication year - 2012
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.1200490
Subject(s) - x linked agammaglobulinemia , primary immunodeficiency , immunodeficiency , bruton's tyrosine kinase , medicine , virology , immunology , tyrosine kinase , immune system , receptor
The importance of pathogen-specific humoral immunity was recognized from the early days of immunology. However, that integrity of humoral immunity is essential to protect against life-threatening infections was established with the discovery of the first primary immunodeficiency disease (PID). In
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