Comment on “Dermatitis Herpetiformis Sera or Goat Anti–Transglutaminase-3 Transferred to Human Skin-Grafted Mice Mimics Dermatitis Herpetiformis Immunopathology” | Zendy

Emiliano Antiga | Zendy; Marzia Caproni | Zendy; Paolo Fabbri | Zendy

Open Access

Comment on “Dermatitis Herpetiformis Sera or Goat Anti–Transglutaminase-3 Transferred to Human Skin-Grafted Mice Mimics Dermatitis Herpetiformis Immunopathology”

Author(s) -

Emiliano Antiga,

Marzia Caproni,

Paolo Fabbri

Publication year - 2011

Publication title -

the journal of immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.737

H-Index - 372

eISSN - 1550-6606

pISSN - 0022-1767

DOI - 10.4049/jimmunol.1190031

Subject(s) - dermatitis herpetiformis , tissue transglutaminase , immunopathology , medicine , dermatology , human skin , immunology , pathology , biology , enzyme , biochemistry , disease , genetics

By passive transfer of anti–transglutaminase-3 (TG3) Abs to SCID mice engrafted with normal human skin, Zone et al. ([1][1]) reproduced the immunopathological pattern of dermatitis herpetiformis (DH), confirming the answer to a long-standing question regarding the source of IgA in DH skin.

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