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Comment on “Acid-Sensing Ion Channels Contribute to the Effect of Acidosis on the Function of Dendritic Cells”
Author(s) -
Xia Li,
FengLai Yuan,
Qing-Yi Zhao,
Weiguo Lü,
Jianping Li,
Cheng-Wan Li
Publication year - 2011
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.1190019
Subject(s) - function (biology) , acid sensing ion channel , acidosis , ion channel , chemistry , biophysics , microbiology and biotechnology , neuroscience , biology , medicine , biochemistry , receptor
We read the interesting paper by Dr. Tong and colleagues ([1][1]) on the role of acid-sensing ion channels (ASICs) in the maturation of dendritic cells (DCs) induced by acidosis. The study sought understanding of the molecular mechanisms by which DCs detect changes in extracellular pH in a sensitive

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