Krüppel-like Factors in Lymphocyte Biology | Zendy

Geoffrey T. Hart | Zendy; Kristin A. Hogquist | Zendy; Stephen C. Jameson | Zendy

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Krüppel-like Factors in Lymphocyte Biology

Author(s) -

Geoffrey T. Hart,

Kristin A. Hogquist,

Stephen C. Jameson

Publication year - 2012

Publication title -

the journal of immunology

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.737

H-Index - 372

eISSN - 1550-6606

pISSN - 0022-1767

DOI - 10.4049/jimmunol.1101530

Subject(s) - krüppel , transcription factor , microbiology and biotechnology , function (biology) , lymphocyte , biology , homeostasis , cellular differentiation , immunology , genetics , gene

The Krüppel-like factor family of transcription factors plays an important role in differentiation, function, and homeostasis of many cell types. While their role in lymphocytes is still being determined, it is clear that these factors influence processes as varied as lymphocyte quiescence, trafficking, differentiation, and function. This review will present an overview of how these factors operate and coordinate with each other in lymphocyte regulation.

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