Open AccessCross-Priming: Its Beginnings
Author(s) -
Federico Carbone,
William R. Heath
Publication year - 2010
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.1090065
Subject(s) - priming (agriculture) , psychology , biology , botany , germination
Our modern understanding of the way that T cells identify target Ag, as a foreign peptide bound to cell-surface molecules encoded within the MHC, can be traced back to the seminal studies in the mid-1970s by Rolf Zinkernagel and Peter Doherty. In their paradigm-shifting “altered-self” hypothesis
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