Open AccessThe Discovery of Immunological Tolerance: Now More Than Just a Laboratory Solution
Author(s) -
Kathryn J. Wood,
Andrew Bushell,
Nick D. Jones
Publication year - 2009
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.0990108
Subject(s) - immunology , immune system , biology , immune tolerance , computational biology
The discovery of acquired immunological tolerance demonstrated unequivocally that immune responses against a defined set of Ags could be abolished, or at least attenuated, using a biological approach. This important series of experiments by Billingham, Brent, and Medawar ([1][1]), using a
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