Open AccessTurning the Tide of Lymphocyte Costimulation
Author(s) -
Yuwen Zhu,
Lieping Chen
Publication year - 2009
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.0990006
Subject(s) - immunology , lymphocyte , biology
The interaction between the T cell and the APC is the pivotal step that controls a series of events, including T cell activation, cell division, and effector differentiation. During the 1980s, with cloning and crystallization of MHC and the TCR locus, the specificity of T cell activation was
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