Open AccessSmall RNAs Guide Hematopoietic Cell Differentiation and Function
Author(s) -
Francisco Navarro,
Judy Lieberman
Publication year - 2010
Publication title -
the journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.737
H-Index - 372
eISSN - 1550-6606
pISSN - 0022-1767
DOI - 10.4049/jimmunol.0902567
Subject(s) - haematopoiesis , microrna , biology , function (biology) , transformation (genetics) , computational biology , microbiology and biotechnology , gene , cancer research , genetics , stem cell
MicroRNAs (miRNAs) are key regulators of gene expression that help direct normal differentiation and malignant transformation of hematopoietic cells. This review summarizes our current knowledge of how miRNAs function in normal and malignant hematopoiesis and how miRNAs might be applied for disease treatment.
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