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Purpose: Sentinel lymph node (SLN) biopsy has been widely used in the management of melanoma and breast cancer. The aims of this study were (1) to compare the results obtained with the different injection, intraoperative sentinel node evaluation, and postoperative evaluation; and (2) to determine the reliability of SLN to predict the regional lymph node status. Methods: We prospectively studied selected 162 female primary breast cancer patients from Jun. 1999 to Apr. 2003. For identification of sentinel lymph node, Tc99m-antimony trisulfate was used as a tracer with two injection methods and SLN biopsy using a gamma-detection probe was done after breast lymphoscintigraphy. Frozen section biopsy or touch-print cytology was done for intraoperative evaluation. If a SLN biopsy was free of metastasis by permanent hematoxylin and eosin (HE6:103-108)

Prospective Study of 162 Sentinel Lymph Node Biopsies in Breast Cancer: Usefulness of Ultrasonography in Patients Selection