Lentivirus-Mediated Short-Hairpin RNA Targeting Protein Phosphatase 4 Regulatory Subunit 1 Inhibits Growth in Breast Cancer | Zendy

Yuying Qi | Zendy; Tinghui Hu | Zendy; Kai Li | Zendy; Renqing Ye | Zendy; Zuodong Ye | Zendy

Open Access

Lentivirus-Mediated Short-Hairpin RNA Targeting Protein Phosphatase 4 Regulatory Subunit 1 Inhibits Growth in Breast Cancer

Author(s) -

Yuying Qi,

Tinghui Hu,

Kai Li,

Renqing Ye,

Zuodong Ye

Publication year - 2015

Publication title -

journal of breast cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1

H-Index - 36

eISSN - 2092-9900

pISSN - 1738-6756

DOI - 10.4048/jbc.2015.18.3.218

Subject(s) - small hairpin rna , gene knockdown , microbiology and biotechnology , cell growth , cell cycle , apoptosis , flow cytometry , mtt assay , western blot , biology , chemistry , biochemistry , gene

Protein phosphatase 4 regulatory subunit 1 (PP4R1), as an interaction partner of the catalytic serine/threonine-protein phosphatase 4 catalytic subunit has been shown to involve in cellular processes and nuclear factor κB signaling. However, the functions of PP4R1 in human breast cancers remain unclear. This study is designed to explore the effect of PP4R1 knockdown on the biological characteristics of breast cancer cells.

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