Factors contributing to suboptimal tumour preservation in breast carcinoma specimens at a tertiary health care setting in Sri Lanka | Zendy

H. D. Wijesinghe | Zendy; R. P. J. C. Nandasena | Zendy; J. Fernando | Zendy; M. D. S. Lokuhetty | Zendy

Open Access

Factors contributing to suboptimal tumour preservation in breast carcinoma specimens at a tertiary health care setting in Sri Lanka

Author(s) -

H. D. Wijesinghe,

R. P. J. C. Nandasena,

J. Fernando,

M. D. S. Lokuhetty

Publication year - 2016

Publication title -

sri lanka journal of surgery/sri lanka journal of surgery

Language(s) - English

Resource type - Journals

eISSN - 2279-2201

pISSN - 0379-8240

DOI - 10.4038/sljs.v34i2.8260

Subject(s) - sri lanka , medicine , medical journal , work (physics) , family medicine , ceylon , medical education , tanzania , socioeconomics , sociology , mechanical engineering , computer science , engineering , programming language

21 (14%) of BCS showed STP. STP correlated positively with delay in specimen receipt to the laboratory of ≥1 day (p=0.002) and increased distance from tumour to surgical resection margin (p=0.037). There was no correlation with type of surgery (wide local excision vs. mastectomy) (p=1.000), tumour size (p=0.698) or delayed specimen dissection at the laboratory of >1 day (p=0.191). Immunohistochemistry (IHC) was performed on 15/21 BCS with STP and showed positive results for oestrogen (14/15 93.3%), progesterone (13/15 – 86.7%) and HER2 (4/15 – 26.7%) receptors.

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