Confirmation of mosaic trisomy 22 in an infant with failure to thrive | Zendy

Kavinda Dayasiri | Zendy; Deepthi De Silva | Zendy; Kumudu Weerasekara | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Confirmation of mosaic trisomy 22 in an infant with failure to thrive

Author(s) -

Kavinda Dayasiri,

Deepthi De Silva,

Kumudu Weerasekara

Publication year - 2018

Publication title -

sri lanka journal of child health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.153

H-Index - 6

eISSN - 2386-110X

pISSN - 1391-5452

DOI - 10.4038/sljch.v47i2.8488

Subject(s) - medical journal , sri lanka , scopus , medicine , publishing , transparency (behavior) , publication , open access publishing , library science , open access journal , family medicine , political science , medline , south asia , law , history , ethnology , computer science

Chromosome mosaicism is defined as the presence of two or more karyotypically different cell lines in an individual. These two cell lines occur as a post zygotic event but other mechanisms are also described. Mosaicism is associated with the live birth of infants with chromosome anomalies that are not detected in non-mosaic forms and the mosaicism may be present at low levels in tissues making cytogenetic confirmation difficult. In some cases, the mosaicism is confined to a single tissue adding to the complexity of diagnosis. We report a child with clinical features of mosaicism in whom the diagnosis of mosaic trisomy 22 was confirmed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research